Summary: T8 - Sequencing Genes and Genomes
What is this TP about?
This TP introduces methods used to determine the exact nucleotide sequence of genes and genomes.
Sequencing Methods
- Sanger sequencing
- Next-generation sequencing (NGS)
Role of Bioinformatics
- Sequence alignment
- Genome assembly
- Gene annotation
- Variant detection
Key Take-Home Message
Sequencing transforms DNA into interpretable biological information.
Literature
Brown T. Gene Cloning and DNA Analysis - An Introduction 8ed (2020)
- Chapter 10 Sequencing Genes and Genomes video
- Chapter 12 Studying Genomes
- Chapter 13 Studying Transcriptomes and Proteomes